黄文才 副教授
四川大学化工学院制药与生物工程系
云顶集团3118acm的联系方式：成都市一环路南一段24号四川大学化工学院（邮编610065）
e-mail: hwc@scu.edu.cn
教育背景
1993. 9 -- 1997. 7成都科技大学有机化工专业工学学士
1997. 9 -- 2000. 7四川大学应用化学专业工学硕士
2000. 9 -- 2003. 7四川大学药物化学专业理学博士
工作简历
2003. 9 -- 2005. 9中科院上海药物研究所博士后
2005. 10 --至今四川大学化工学院制药与生物工程系讲师/副教授/硕士生导师
2014. 9 -- 2015. 9美国弗吉尼亚大学化学系访问学者
教学工作
负责本科生《药物化学》、《化学制药工艺学》及研究生《药品制造工程导论》等课程的教学工作，主编《药物合成反应》（科学出版社，2021），副主编《制药工程技术概论》（化工出版社，2019）。
科研方向
1.小分子荧光探针的研究
2.药物研制与开发
3.绿色化学制药工艺研究
主持或参加国家自然科学基金、广东省-教育部产学研结合项目、四川大学校青年科研基金及多项企业合作开发项目。
代表性科研成果
1.zhang dan, wang sifan, yang fangxi, qi qingrong, li yanfang*,huang wencai*. a fluorescent probe for alkylating agents and its quantification of triflate as a genotoxic impurity. chem. commun., 2023,59(15): 2130-2133.
2.zhang dan, wang sifan, yang fangxi, li zicheng,huang wencai*. visual inspection of acidic ph and bisulfite in white wine using a colorimetric and fluorescent probe. food chem.. 2023,408: 135200.
3.zhang zichang, zhang dan, qi qingrong, li zicheng,huang wencai*. a colorimetric and fluorometric probe for phenylhydrazine and its application in real samples. chem. commun., 2022,58(61): 8540-8543.
4.zhang zichang, tu liangping, zhang dan, li zicheng,huang wencai*. comparative studies on the absorption and fluorescence responses of hemicyanine to hso3-, cn-, hs-and clo-. spectrochim. acta a, 2022,269: 120781.
5.tu liangping, liu jian, zhang zichang, qi qingrong, yao shun,huang wencai*. micheal addition reaction-based fluorescent probe for malononitrile detection and its applications in aqueous solution, living cells and zebrafish. analyst,2021,146(7): 2221-2228.
6.wang shun, liu jian,song linjiang, qi qingrong*, li zicheng, huang wencai*.a selective and sensitive near-infrared fluorescent probe for in vivo real time tracking of exogenous and metabolized hydrazine, a genotoxic impurity. j. mater. chem. b, 2020,8(45): 10353-10359.
7.zhang yi, tu liangping, lu lingling, li yuxiao, song linjiang,* qi qingrong, song hang, li zicheng,huang wencai*.screening and application of boron difluoride complex of curcumin as a colorimetric and ratiometric fluorescent probe for bisulfite. anal. methods, 2020,12(11): 1514-1521.
8.liu jian, li tao, wang shun, qi qingrong, song hang, li zicheng, yang li*,huang wencai*. a sensitive and selective fluorescent probe for hydrazine with a unique nonaromatic fluorophore. rsc adv.,2020,10: 5572-5578.
9.li tao, liu jian, song linjiang, li zicheng, qi, qingrong*,huang wencai*. a hemicyanine-based fluorescent probe for hydrazine detection in aqueous solution and its application in real time bioimaging of hydrazine as a metabolite in mice. j. mater. chem. b, 2019,7: 3197-3200.
10.li yuan, ji yu-xin, song lin-jiang, zhang yi, li zi-cheng, yang li,huang wen-cai*. a novel bf2-curcumin-based fluorescent chemosensor for detection of cu2 in aqueous solution and living cells. res. chem. intermed., 2018,44(9): 5169-5180.
11.zhou ji-cai, zhao lei, li yuan, fu ding-qiang, li zi-cheng,huang wen-cai*. alkynylation of aldehydes mediated by zinc and allyl bromide: a practical synthesis of propargylic alcohols. res. chem. intermed., 2017,43(7):4283-4294.
12.zhang yun-hao, wu ming-yue,huang wen-cai*. silica gel-promoted practical synthesis of oxindole-nitrones from diazooxindoles and nitrosoarenes under solvent-free conditions. rsc adv., 2015,5(128): 105825-105828.
13.huang wen-cai, liu winnie, wu xue-dan, ying jun, pu lin*. highly enantioselective alkyne addition to aliphatic, aromatic and vinyl aldehydes by using zn,ipri, h8binol and ti(oipr)4. j. org. chem., 2015,80(22): 11480-11484.
14.xie j. y., liu j. q., zhang y. h., li j. j., li z. c.,huang w. c.*. an improved preparation of 2, 6-di-tert-butyl-4-methylphenol. org. prep. proced. int., 2015,47(3): 236-241.
15.liu junqiang, mi chenggen, tang xuemei, cao yuan, li zicheng,huang wencai*. facilemicrowave-assisted synthesis of substituted benzofuran derivatives. res. chem. intermed., 2014,40(5): 2083-2090.
16.yang li, lei hua, mi cheng-gen, liu huan, zhou tian, zhao ying-lan, lai xiao-yun, li zi-cheng, song hang,huang wen-cai*. synthesis, antiproliferative activities and in vitro biological evaluation of novel benzofuransulfonamide derivatives. bioorg. med. chem. lett., 2011,21(18): 5389-5392.
17.luo xin-feng, he ling, yin hai-bin, zheng hu, bei di, deng jin-jin,huang wen-cai*. efficient acylation and one-pot synthesis of dehydroandrographolide succinate on a large scale assisted with microwave radiation. synth. commun., 2009,39(19): 3444-3452.
18.huang wencai, zheng hu, weng lingling. synthesis of tetracycline analogs and their bone affinities. chin. chem. lett., 2008,19(1): 19-22.
19.黄文才,张丹,程度,张春红,陈文芝,雷华.一种三水合3-氨基丙基胺乙基硫代磷酸的合成方法.中国发明专利, zl 201110152336.6, 2014-2-26.
